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Devon ear wax removal centre

ear syringing Devon, Ear syringing Exeter, Ear syringing Sidmouth, Ear syringing Teighnmouth,

Devon ear wax removal centre

Available at the Honiton hearing centre near Exeter

 

Ear wax removal doesn’t have to be a chore. We are a fully accredited ear wax removal specialist centre that covers the whole of Devon and Somerset, handily located in Honiton close to Exeter.  We are a family run business and cherish that we serve our local community, also people from a far.  We use the traditional ”Ear syringing” technique, which is actually called water irrigation and isn’t anything like a carry on film. You can watch Colin Eaton talk about ear syringing here in this video. He will explain in detail what that was all about and what is now the gold standard.

Devon Microsuction

The Gold standard these days is called Microsuction or Micro-Suction depending where you read. It is basically a very very small hoover type of device that gently sucks up the ear wax in a safer manor than hitting the ear with pressured water which they did in the bad old days. Ears are very delicate, with todays techniques the risk is a lot lower.

You can watch how Micro-Suction is performed by watching this video here conducted again by Colin Eaton who is the lead audiologist here at the Honiton hearing centre.

Devon ear wax removal centre

We look forward to seeing you if you haven’t been here before, if you could please call Sam on reception or you can make an online booking by clicking here. 

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Devon hearing centre

ear syringing Devon, Ear syringing Exeter, Ear syringing Sidmouth, Ear syringing Teighnmouth,

Devon Hearing Centre

 

The Devon Hearing Centre is located at the Honiton hearing centre close to Exeter.

 

 A truly family owned and run hearing centre for Devon. Specialising in ear wax removal using the Microsuction technique. Honiton hearing also use the traditional service of ear irrigation using warm water which for some impacted ear wax can be an easier way to remove if stubbornly in the ear. This is sometimes called ear syringing, although the syringe hasn’t been uses for some decades. It’s funny how sayings can last long after that way of doing things have long gone.

Devon hearing centre

To watch how Microsuction is used, you can watch how Colin Eaton from the Honiton hearing centre uses the equipment. It is very simply a micro hoover that attaches to the ear wax and gently removes it. No pain, no water and very quick. Click here to see the video.

 

For an appointment at the Honiton hearing centre please call Sam on reception.

 

ear syringing Devon, Ear syringing Exeter, Ear syringing Sidmouth, Ear syringing Teighnmouth,

Ear syringing in Devon at the Honiton hearing centre

 

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Ear wax removal Devon

ear syringing Devon, Ear syringing Exeter, Ear syringing Sidmouth, Ear syringing Teighnmouth,

Ear wax removal Devon

Ear wax removal Devon by Colin Eaton the local audiologist covering Devon and Somerset

 

Colin Eaton the ear wax specialist based in Honiton located between Exeter and Tiverton, is the West country leading ear wax remover. Using Microsuction, or the traditional water irrigation method (ear syringing), the wax removal is painless, simple and effective. With 1000’s of satisfied customers Colin knows how to make you feel at ease and relaxed.

 

To see Colin in action and to watch ear wax removal using Microsuction click here to see the video.

 

Colin Eaton works with his wife Sam making the company a family run affair and totally independent.  The difference between a large company and a local family run company is we make you feel you are wanted and valued rather than just a number.  We  love to see new clients and our existing clients hearing clearer and wax free. If you need ear wax removing in the county of  Devon book your appointment soon.

Ear wax removal Devon

 

 

Honiton Hearing News:

 

Phonak Marvel Receives Gold Stevie Award, Named ‘Innovation of the Year’

Stevie Awards

Phonak announced its Marvel hearing aid solution has won a Gold Stevie Award and was named Innovation of the Year—Consumer Products Industries in the 2019 International Business Awards. According to comments obtained from judges, the multifunctional hearing solution received top honors for being “the world’s first hearing aid to combine universal Bluetooth connectivity, lithium-ion rechargeability, and top-rated sound quality into a single device.” The Gold Stevie marks the fourth major product honor awarded to Phonak Marvel this year, placing it among the company’s most highly-awarded products ever, according to Phonak.

iba19_gold_winner

“We are thrilled that Phonak Marvel has received a Gold Stevie award and was named an Innovation of the Year,” said Martin Grieder, Group Vice President, hearing instruments marketing. “Marvel truly is the culmination of so many of our innovations into one product—including rechargeability, universal Bluetooth connectivity, Binaural VoiceStream Technology, and various eSolutions, just to name a few. All this technology works together to produce clear, rich sound quality from the very first fit.”

Devon Microsuction

The Gold Stevie award is the latest product honor awarded to Phonak Marvel this year. In June, Marvel received the 2019 MedTech Breakthrough Award for its ability to fully support stereo audio streaming from Android and iOS devices. Also in June, Phonak eSolutions, optimized for Marvel, was the winner of the 2019 Mobile Business Awards. Phonak Marvel also received a Silver Edison Award in April and was named a 2019 CES Innovation Award Honoree in January.

A record total of more than 4,000 nominations from organizations of all sizes and in virtually every industry were submitted this year for consideration in a wide range of categories, including Company of the Year, Marketing Campaign of the Year, Best New Product or Service of the Year, Startup of the Year, Corporate Social Responsibility Program of the Year, and Executive of the Year, among others.

Wax removal Exeter

Stevie Award winners were determined by the average scores of more than 250 executives worldwide who participated in the judging process from May through early August, according to Phonak’s announcement.

For more information about Phonak Marvel, visit: www.phonak.com. Details about The International Business Awards and the lists of Stevie Award winners are available at: www.StevieAwards.com/IBA.

Source: Phonak, International Business Awards

Images: International Business Awards

 

Devon ear wax removal

Honiton hearing, Keynsham hearing

Devon ear wax removal

 

Devon ear wax removal at the Honiton hearing centre near Exeter. Ear wax removal doesn’t have to be a pain. The Honiton hearing centre are specialist at ear syringing for the Devon area including Tiverton, Lyme bay and Sidmouth. Using the gold standard Micro-Suction technique, your ears will be cleared of wax in no time at all. Painless, easy and quickly without fuss. Devon ear wax removal covers all areas of Devon. If Micro-Suction isn’t what you like then we have the traditional ear syringing method of water irrigating the ear to remove the ear wax. Which ever takes your fancy we can remove ear wax in minutes.

Call reception and speak with Sam, she will book your appointment and Colin Eaton will be the person who you will be doing the wax removal procedure.

Click here to see how Microsuction works at the Honiton hearing centre.

Book early as we do get busy at times through the year!

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Depression and Hearing link

Depression, Somerset, hearing loss, Ear wax removal Somerset, Ear wax removal Devon, Ear wax removal Taunton

Depression and Hearing link, Somerset & Devon

 

Depression and Hearing link, Bristol. Stephen Neal audiologist who is based at the Keynsham hearing centre knows that Depression and hearing can be linked.

Depression and hearing link found by researchers.

New report into depression and hearing has been published. We at the Keynsham hearing centre are well aware of this link and can help with making your hearing a little better.

Somerset hearing and Ear wax removal centre

 

Somerset and Devon hearing and Ear wax removal centre are at the Keynsham hearing centre and the Honiton hearing centre. These are independent hearing and ear wax specialist covering Bath, Bristol, & Somerset and Devon.  If you are having issues with hearing in general we can conduct a hearing test at Keynsham or Honiton. The comprehensive hearing test will take around an hour of your time, but the results will be know there and then putting you in control of your hearing. We can then discuss what hearing instrument (hearing aid) you may need if required.  There could be other issues at play if you are not hearing as well as you think you should be. We can before the test look to see if you have any ear wax present. Ear wax isn’t usually an issue, we all need a little for good ear health. However in some cases excessive ear wax build up can become an issue and if you have excessive ear wax we will clear this before any test is conducted.

Depression and Hearing link, Somerset and Devon

Ear wax removal is very easy and painless. We use the Microsuction ear wax removal method as this really is the gold standard of ear wax removal. We also can use the older method of ear wax removal called irrigation or some may know this as ear syringing. This method uses warm water to gently irrigate the ear to help release the ear wax out from the ear.

You can watch our ear wax removal here

 

So if you are having some hearing issues and would like afamily run professional ear wax removal service then book an appointment. We can discuss at the appointment any of the issues at length. After all we are all ears!

 

Ear wax removal Somerset and Devon

 

Ear wax removal.co.uk/ News:

Bringing world wide news on hearing to our local area.

 

Study Shows Older Adults with Hearing Loss at Higher Risk for Depression

 

Hearing loss is linked to depression

Chalfont hearing centre

The results of a study investigating the connection between hearing loss and depression found that older adults with some form of hearing loss were 47% more likely to also have depression symptoms, according to an article in Reuters

East Devon Hearing centre

Originally published in The Gerontologist, the research reviewlooked at 35 previous studies encompassing 147, 148 participants, who were at least 60 years old.

“We know that older adults with hearing loss often withdraw from social occasions, like family events because they have trouble understanding others in noisy situations, which can lead to emotional and social loneliness,” lead study author Blake Lawrence of the Ear Science Institute Australia, in Subiaco, and the University of Western Australia in Crawley, was quoted as saying in Reuters. 

Additionally, the article goes on to add that the brain may work harder to interpret sound from a weaker auditory signal, draining resources needed to maintain working memory or other cognitive functions. A weaker signal may also cause the “reorganization” of neural pathways, potentially changing the way depression is regulated in the brain.

Ear syringing Devon

In a new white paper produced by The Hearing Review and sponsored by Hamilton CapTel, “Depression, Hearing Loss, and Treatment with Hearing Aids,” audiologist and educator Victor Bray, PhD, reviews previous landmark studies as well as more recent research into the complex relationship between hearing loss and depression. The paper helps identify patient populations who might benefit most from hearing devices. Additionally, Dr Bray’s webinar “Depression, Hearing Loss, and Treatment with Hearing Aids,” discusses the risk factors for depression among people with hearing loss as well as why hearing care providers should screen for depression when risk factors are present.

Original Paper: Lawrence BJ, Jayakody DMP, Bennett RJ, Eikelboom RH, Gasson N, Friedland PL. Hearing loss and depression in older adults: a systematic review and meta-analysisThe Gerontologist. 2019:1-19. DOI: https://doi.org/10.1093/geront/gnz009

Source: Reuters, The Hearing Review, The Gerontologist

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Hearing aids for Devon and Somerset

Ear wax removal Bath, Ear wax removal Honiton, ear wax removal Devon

Hearing aids for Devon and Somerset

 

Hearing aids for Bristol and Bath by Stephen Neal.  Stephen prides himself on being at the vanguard of hearing technology. Based at the Keynsham hearing Centre, Stephen Neal is a lead audiologist and is first class at keeping up with the new tech that comes out constantly.  Today we he is looking at the recently announced Phonak Marvel. For those who don’t know what this product is here is a sample from their Press release.

”In October 2018, Phonak introduced Marvel, a hearing aid family that’s said to “combine all the top-requested features from hearing aid wearers” into one solution.

Hearing aids for Devon and Somerset

According to Phonak, this technology also helps to improves accessibility to hearing care by empowering consumers to benefit from a suite of smart apps that connect hearing aid wearers with their hearing care professional via smartphone. These include video chat, instant feedback regarding their wearing experience, remote fine-tuning from anywhere in the world, and real-time, voice-to-text transcription of phone calls”.

Hearing aids Honiton, Devon

Sounds good?  We think so and we are pleased that Phonak has won a prestigious award saying that they agree too. If this Phonak product sounds like something you may like more info on then please let us know and we could arrange an appointment to see if this would be right for you.

See the rest of the info on the Phonak Marvel product bellow.

Check out  our earwax removal video here.

 

Earwax removal News: 

Phonak Marvel Wins Silver Edison Award for Hearing Aid Design Technology

Phonak Marvel hearing aid technology also improves accessibility to hearing care by empowering consumers to benefit from a suite of smart apps that instantly connect hearing aid wearers with their hearing care professional via their smartphone.

Phonak Marvel available at the Honiton hearing centre Devon

Phonak Marvel, said to be “the world’s first hearing aid” to combine clear sound quality with universal “made for all” Bluetooth connectivity, received a Silver Award in the hearing aid design technology category at the Edison Awards gala in New York City, the hearing aid manufacturer announced. The Edison Awards, named after Thomas Alva Edison, recognizes and honors innovators and innovations.

In October 2018, Phonak introduced Marvel, a hearing aid family that’s said to “combine all the top-requested features from hearing aid wearers” into one solution.

Ear wax removal Devon

According to Phonak, this technology also helps to improves accessibility to hearing care by empowering consumers to benefit from a suite of smart apps that connect hearing aid wearers with their hearing care professional via smartphone. These include video chat, instant feedback regarding their wearing experience, remote fine-tuning from anywhere in the world, and real-time, voice-to-text transcription of phone calls.

All nominations were reviewed by the Edison Awards Steering Committee and the final ballot sent to an independent judging panel. The judging panel was comprised of more than 3,000 professionals from the fields of product development, design, engineering, science, marketing, and education, including professional organizations representing a wide variety of industries and disciplines.

Hearing aids for Devon and Somerset

For more information on the 2019 Edison Awards, please visit: www.edisonawards.com.  Applications for the 2020 awards will open in August 2019.

 Source: Phonak, Edison Awards

Images: Phonak

Ear wax removal Devon and Somerset

Devon ear wax removal, Somerset ear wax removal, Sidmouth ear wax removal, Bristol ear wax removal

Ear wax removal Devon and Somerset

 

Ear wax removal Devon and Somerset is available at the Honiton hearing centre and the Keynsham hearing centre. If you are suffering from excessive wax build up in the ear or ears we can come to your aid. Using Micro-Suction or the traditional irrigation technique, (some call it ear syringing), it only take a few mins to painlessly remove excess ear wax. Please click here to see how Micro-Suction works via our new online video on the Honiton Hearing website.

To see how ear wax removal at the Keynsham centre please click here. 

If you live in Tiverton area then contact us for Ear wax removal near Tiverton Devon

Honiton hearing centre also conduct lots of other ear related issues such as hearing tests, dispensing the very latest digital hearing aids along with hearing aid servicing and setting up of new hearing aids after you purchase them. If you need any of our services please book in using our online booking calendar or call Sam on reception.

 

Honiton & Keynsham news:

Philips Hearing Aids Introduced by Demant

Published on 

 

Philips-Hearing-Aids-Honiton-Hearing-Devon

Honiton hearing Devon

Demant, Copenhagen, Denmark, has announced the introduction of Philips branded hearing aids to the global hearing aid market, according to a press release from the company. A new player, the Philips brand is entering the hearing healthcare market with a complete range of premium hearing aids, accessories, and applications to best serve hearing aid users. Demant states Philips Hearing Solutions will quickly become a trusted brand with hearing care providers and users, as it has great potential around the world to present unique opportunities for hearing care professionals in an ever-evolving market.

Ear wax removal Devon and Somerset

In August, Demant  announced a licensing agreement with Philips, which is headquartered in Eindhoven, The Netherlands, to bring Philips-branded solutions to the hearing healthcare market.  Demant (formerly William Demant Holding) is the parent group of Oticon, Sonic, and Bernafon hearing aids, as well as Oticon Medical.

Ear wax removal near Tiverton Devon

“Based on a shared vision of improving the lives of people through innovative healthcare this new cooperation will not only change the way we see hearing healthcare, but also widen the definition of hearing healthcare, supporting healthier lifestyles and active aging,” said Spencer Ramsey, Senior Director of Brand Licensing, Philips, in the press statement. “Combining Demant’s world-leading hearing aid technology with Philips’ global brand presence in healthcare, the cooperation will enrich the hearing healthcare experience.”

The new premium Philips hearing aids—named Philips HearLink—are now available for hearing care professionals in selected countries. The look and feel of the Philips HearLink hearing aids is designed to cater to today’s baby boomer generation with design and usability developed for this expanding market. Philips HearLink users will benefit from connectivity between their hearing aids and the devices they use in their everyday life, such as smartphones and televisions. The hearing aids will reportedly be manufactured by Demant using the Velox-S and Velox platforms, and will be available in a complete range of styles, including RICs, BTEs, ITCs, CICs, and IITs.

Demant President Søren Nielsen provided an overview of the Oticon Opn S and Opn Play at an investor and media presentation.

Søren Nielsen

 

“The Philips hearing aids will provide users with an innovative, future-proof hearing solution,” says Demant President & CEO Søren Nielsen. “We live in an age where user engagement and digital services are shaping the future of healthcare technology. More and more people are conscious of taking control of their own personal healthcare and are using electronic devices to do so. In this light, Philips Hearing Solutions offers new and exciting premium solutions alongside Philips’ healthcare ecosytem, which will attract interest and generate significant benefits to users, ultimately supporting our valued customer base of hearing care professionals.

Bath ear wax removal at the Keynsham Hearing centre

 

“With this partnership, we take connected hearing healthcare to the next level and offer new and exciting solutions within integrated healthcare services to the benefit of both professionals and people suffering from a hearing loss,” continued Nielsen. “Health, caring, and innovation are cornerstones in the vision of both Demant and Philips, which makes the partnership a great match for the future. Furthermore, it will strengthen and add value to both companies’ ambition to improve people’s lives.”

The Philips brand is something of a “back to the future moment” for more seasoned dispensing professionals. Philips was a well-known hearing aid brand in the 1990s, and the company embarked on a technical collaboration with Telex then exited the market just before the turn of the new century when Beltone purchased Philips’ hearing aid technology. The Hearing Review published numerous news and technical articles about Philips technology in the 90s.

Traditionally, hearing aid branding has not played a large role in hearing healthcare; MarkeTrak 9 suggested that less than half of hearing aid users (43%) could identify the brand of their device. However, many experts in the industry believe this is due to change, as more consumers are expected to enter the market and there is continued competition and aggressive marketing among dispensing chains, pharmacies, mass merchandisers, and online retailers. The Philips brand brings with it one of the world’s best known and trusted healthcare and consumer electronics brands.

For further information about Philips Hearing Solutions and a full presentation of the Philips HearLink product range, visit: hearingsolutions.philips.com

Latest digital hearing aids, Devon and Somerset

Devon, are wax removal, batteries, hearing aid, hearing aid batteries, Honiton

Latest digital hearing aids, Devon and Somerset

 

New hearing aids in Devon and Somerset at the Honiton hearing centre and Keynsham, hearing centres. We are used to new hearing aids arriving from various manufacturers all year round, but when something is really new and exciting we love to tell you and our existing clients why we are so excited.

Hearing aids have evolved in recent years. Digital hearing aids have made the devices so small and powerful they are no longer what people expect to see. The huge hearing aid of old is getting less visible these days, the new as powerful hearing aids are now tiny. If you are looking for new hearing aids in Somerset & Devon, we are the place for you!

New hearing aids Devon & Somerset

The tech inside these little wonders are amazing on so many levels. Take one of the many things they can do. They can connect to your mobile phone and you can talk wirelessly without the phone in your hand as if you were talking to a person next to you. The hearing aid is catching your voice and transmitting this to your phone via bluetooth. You can hear perfectly as your hearing aid is in your ear so you don’t have to really listen hard to get what the conversation is. It’s all done without you doing anything. This tech isn’t new, it has been around for some years, but if your hearing aids are not ”Connected” versions, then maybe when you are next due a new set of hearing aids, you can ask to be told of what’s new in this ”Connected” world.

Somerset & Devon hearing aid centres

Colin Eaton & Stephen Neal the lead audiologists at Honiton & Keynsham hearing will be happy to show you and explain all about what is new and on offer. They will also show you how you connect your new digital hearing aid with various tech such as mobile phones, iPads, and the T.V.

Make your appointment with Colin now by calling Sam on reception or use the booking form here.

Make your appointment with Stephen Neal at Keynsham by clicking here.

You can watch how ear wax removal is done by watching one of our videos here.

 

Ear wax removal News:

 

Semtech and Sonova Launch Jointly-Developed Radio System

Digital hearing aids, Devon

Latest Digital hearing aids at the Honiton hearing centre, Devon

Semtech Corporation (Nasdaq: SMTC), a supplier of high-performance analog and mixed-signal semiconductors and advanced algorithms, and Sonova, a developer of hearing care solutions, announced a jointly developed advanced radio system. The ultra-small integrated circuit (IC) is said to be a main component for a new generation of hearing aids, enabling support for multiple radio protocols in the 2.4GHz band, as well as effective operation on very low power, according to the announcement.

New hearing aids Devon and Somerset

“This chip allows Sonova to move in a new direction with our hearing aids,” said Marc Secall, director, research & development, wireless, at Sonova. “The breakthrough radio technology and power management are the game changers for hearing aids. It allows them to support a number of applications that have previously not been possible in a hearing aid, all at low power consumption and low supply voltage. Possible applications span from connectivity to any Bluetooth®-enabled audio device (eg, a smartphone or television) to full duplex audio streaming between hearing aids and connectivity to wireless microphones.”

Ear wax removal Devon & Somerset

“Semtech continues to innovate and create flexible, reliable solutions for challenging applications associated with the best radio frequency connectivity at the lowest power and 0.8V supply voltage,” said Jean-Paul Bardyn, vice president of research and development of Semtech’s wireless and sensing products group. “Sonova has long been a leader for hearing devices. By implementing Semtech’s technology and enabling access to the Cloud, we believe that these devices will enrich the IoT-connected solutions which Semtech is serving with LoRa Technology.”

Source: Semtech, Sonova

Images: Semtech, Sononva

Somerset & Devon ear wax removal

Somerset and Devon ear wax removal

Honiton hearing centre, Devon

 

 

Somerset & Devon ear wax removal are available at the Honiton hearing centre & The Keynsham hearing centres, which caters for all types of hearing loss and ear wax removal. Colin Eaton, the lead audiologist at the Honiton hearing centre has over 15 years audiology expertise to make sure his clients get the best hearing result no matter what the hearing issues are.

Ear wax removal is available by appointment and a limited amount of out of hours appointments are available but please call Sam on reception if you require out of hours.

Somerset & Devon ear wax removal

Comprehensive hearing tests are also available. Please make sure that any ear wax issues are clear before you take the test, if you need ear wax removing prior the test please call reception and make this clear to Sam that you will need ear wax clearing first.

Please call Honiton hearing here

 

Keynsham hearing centre, Somerset

 

Keynsham hearing centre are situated between Bath and Bristol along the A4. Easy parking available. Keynsham hearing are an independent hearing centre specialising in ear wax removal and the very latest digital hearing aids supplied form at least 12 of the worlds leading hearing aid brands.

Somerset & Devon ear wax removal

Keynsham hearing also offer out of hours ear wax removal appointments. To book your appointment please call Anita on reception. Number is here

 

Somerset and Devon ear wax removal News:

Researchers Restore Hearing via Gene Therapy in Deaf Mouse Model

Published on 

In collaboration with the universities of MiamiColumbia, and San Francisco, scientists from the Institut Pasteur, InsermCNRSCollège de FranceSorbonne University, and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness, a hearing disorder that represents one of the most frequent cases of congenital genetic deafness, Institut Pasteur announced on its website. Individuals with DFNB9 deafness are profoundly deaf as they are deficient in the gene coding for otoferlin, a protein which is essential for transmitting sound information at the auditory sensory cell synapses. By carrying out an intracochlear injection of this gene in an adult DFNB9 mouse model, the scientists successfully restored auditory synapse function and hearing thresholds to a near-normal level. These findings, published in the journal PNAS, open up new avenues for future gene therapy trials in patients with DFNB9.

The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced. © Institut Pasteur

Over half of nonsyndromic profound congenital deafness cases have a genetic cause, and most (~80%) of these cases are due to autosomal recessive forms of deafness (DFNB). Cochlear implants are currently the only option for recovering hearing in these patients.

Somerset & Devon ear wax removal

Adeno-associated viruses (AAVs) are among the most promising vectors for therapeutic gene transfer to treat human diseases. AAV-based gene therapy is a promising therapeutic option for treating deafness but its application is limited by a potentially narrow therapeutic window. In humans, inner ear development is completed in utero and hearing becomes possible at approximately 20 weeks of gestation. In addition, genetic forms of congenital deafness are generally diagnosed during the neonatal period. Gene therapy approaches in animal models must therefore take this into account, and gene therapy efficacy must be demonstrated following a gene injection when the auditory system is already in place. In other words, therapy must reverse existing deafness. The team led by Saaïd Safieddine, a CNRS researcher in the Genetics and Physiology of Hearing Unit (Institut Pasteur/ Inserm) and coordinator of the project, used a mouse model of DFNB9, a form of human deafness that represents 2-8% of all cases of congenital genetic deafness.

DFNB9 deafness is caused by mutations in the gene coding for otoferlin, a protein that plays a key role in transmitting sound information at the inner hair cell synapses. Mutant mice deficient in otoferlin are profoundly deaf as these synapses fail to release neurotransmitters in response to sound stimulation, despite the absence of detectable sensory epithelial defects. DFNB9 mice therefore constitute an appropriate model for testing the efficacy of viral gene therapy when it is administered at a late stage. However, as AAVs have limited DNA packaging capacity (approximately 4.7 kilobase (kb)), it is difficult to use this technique for genes whose coding region (cDNA) exceeds 5 kb, such as the gene coding for otoferlin, which has a 6 kb coding region. The scientists have overcome this limitation by adapting an AAV approach known as dual AAV strategy because it uses two different recombinant vectors, one containing the 5’-end and the other the 3’-end of the otoferlin cDNA.

A single intracochlear injection of the vector pair in adult mutant mice was used to reconstruct the otoferlin coding region by recombining 5′ and 3′-end DNA segments, leading to long-term restoration of otoferlin expression in the inner hair cells, and then restored hearing.

Somerset & Devon ear wax removal

The scientists have therefore obtained initial proof of the concept of viral transfer of fragmented cDNA in the cochlea using two vectors, showing that this approach can be used to produce otoferlin and durably correct the profound deafness phenotype in mice.

The outcomes achieved by the scientists suggest that the therapeutic window for local gene transfer in patients with DFNB9 congenital deafness could be wider than thought, and offers hope of extending these findings to other forms of deafness. These results are the subject of a patent application filed.

In addition to the institutions mentioned in the first paragraph, this research was funded by the French Foundation for Medical Research, the European Union (TREAT RUSH), and the French National Research Agency (EargenCure and Lifesenses LabEx).

Original Paper: Akil O, Dyka F, Calvet C, et al. Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model. PNAS. 2019. DOI: https://doi.org/10.1073/pnas.1817537116

Source: Institut Pasteur, PNAS

Image: Institute Pasteur

 

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Devon hearing aids & ear wax removal

Honiton, Keynsham, kingsbridge, Wax, removal, ears,

Devon hearing aids & ear wax removal

 

Devon hearing aids and ear wax removal at the Honiton hearing centre

 

If you are in Devon and in need of ear wax removal services then the Honiton hearing centre is the place to go. Colin Eaton the lead audiologist specialises in ear wax removal using the Microsuction as well as the traditional water irrigation technique. Please go here to watch how the the Micro-suction technique look like and sounds like. The video will show how easy and painlessly Micro-Suction is. n

Devon hearing aids

The Honiton hearing centre are a family owned independent hearing centre and cover the whole of Devon, but are in an easy drive from Lyme bay, Sidmouth and Exeter. The very latest digital hearing aids are dispensed at Honiton. After a full spectrum hearing test Colin will sit down and discuss what the hearing test results are and will then go on to show you what your options are to get back to hearing more like normal. You will be amazed at what the latest digital hearing aids can do these days.

Trial Hearing aids Devon

If you have never had a hearing aid or a set of hearing aids and would like to trial them before you purchase please ask Colin. Trial hearing aids are available from most manufacturers.

 

Ear wax removal news:

 

Widex Announces TV PLAY and RedDot Award Honour

Widex TV PLAY.

Widex A/S, Lynge, Denmark, the privately-owned Danish hearing aid company, has announced the launch of WIDEX TV PLAY, a high-end TV accessory and streaming solution for WIDEX EVOKE hearing aids. The sleek and versatile TV PLAY received the Red Dot Design Concept Award last Friday, September 28, for its pleasing design.

WidexWidex has also been honored as a leader in innovation in the RedDot Design Ranking for Design Concepts. The company placed number 4 out of 15 companies in the Americas and Europe region in recognition of its pursuit of design excellence over the past 5 years, reports the company.

Shipments of TV PLAY will start in November.

A valuable accessory for hearing aid users. A 2017 Nielsen survey1 reported that the US 65+ population consumes a daily average of 6 hours and 57 minutes of TV. Despite the growing number of mobile and web-based streaming services, watching TV is more popular than ever. But for some, it’s a struggle to hear the TV. Hearing aid users can find it hard to hear the TV over the other sounds in the room. In fact, some studies suggest that 78% of hearing aid users have trouble understanding things on the TV.

Designed for ease of use. According to Widex, TV PLAY lets hearing aid users enjoy great TV sound effortlessly through their hearing aids by providing direct streaming to both ears. TV PLAY is designed for fast and easy to set up, intuitive to control, and delivers outstanding and stable sound.

TV PLAY drops the “boxy” look of many TV streamers and instead has a futuristic design that blends in with modern homes. And if you prefer to have TV PLAY out of sight, the slim and discrete design fits behind flat screen TVs with no trouble, according to the company.

“At Widex we work to ensure that hearing aid users get the most of all aspects of life,” said Widex President and CEO Jørgen Jensen in a press statement. “We know that TV is an important part of staying in touch with the world around them through news and entertainment programs. TV PLAY gives them a better and more stable experience that also looks great in their living rooms.”

Maximum streaming stability. With Widex’s patent-pending dual-antenna technology, TV PLAY is said to offer maximum streaming stability. An easy-to-use app lets users balance the volume of the TV sound with ambient sounds and conversations—or choose just to hear the sound from the TV.

1. Nielsen. Total Audience Report Q2 2017. November 16, 2017. Available at: https://www.nielsen.com/us/en/insights/reports/2017/the-nielsen-total-audience-q2-2017.html

Source: Widex A/S